This Grand Rounds delves into the controversial topic of brain death and organ procurement. Dr. Heidi Klessig shares her unsettling experiences and questions the definitions and criteria surrounding brain death, highlighting inconsistencies in medical guidelines and ethical concerns. She discusses high-profile cases that challenge the notion of irreversible death and the implications for organ donation practices. The session raises awareness about the potential for misdiagnosis and the ethical dilemmas faced by families and healthcare professionals. Ultimately, it calls for a reevaluation of the definitions and practices surrounding organ donation.