Read about the class:

This Grand Rounds begins with a simple but unsettling observation: when death records are examined carefully, Acute Kidney Injury emerges as the largest and most consistent signal beginning in 2021. This was not a subtle shift. In state after state, kidney failure appears with a frequency that far exceeds historical norms, yet it remained largely absent from public discussion and institutional review.

Reading the Records Without Filters

Using 1.6 million non-redacted death certificates from Massachusetts, Connecticut, and Minnesota, John Beaudoin Sr. explains how standard statistical methods often smooth away critical information. When records are instead reviewed visually and temporally—one after another, in sequence—patterns become impossible to ignore. Nearly every state shows a dramatic increase in kidney-related deaths starting in 2021, with 49 out of 50 states reflecting the same directional change.

When Timing Reveals What Statistics Hide

A major portion of the lecture focuses on timing. Once paradoxes and confounders are adjusted for, the signal changes shape. Distinct seasonal spikes appear that align with COVID-era hospitalizations, alongside a separate linear rise that moves toward a steady state. These are not random fluctuations. They are different signals layered on top of each other, only visible when the data is examined in time order rather than averaged across populations.

COVID-Era Medicine and Kidney Injury

The analysis connects these patterns directly to COVID-era medical practices. Hospital protocols introduced during the pandemic, including drug usage patterns and treatment incentives, coincided precisely with the observed kidney injury signals. The lecture walks through how these protocols interacted with patient outcomes, raising serious questions about iatrogenic harm during this period and why kidney injury was not flagged sooner as a central warning sign.

Why Correlation Is Not Enough

A core argument of the presentation is that statistics alone cannot resolve questions of causality. Temporal Based Medicine requires physicians to examine medical records forensically, tracing what occurred before, during, and after specific interventions. This record-level approach avoids abstraction and forces accountability by focusing on real patients, real timelines, and real outcomes.

What Could Have Been Known—and When

One of the most striking conclusions is how quickly clarity could be achieved. According to the framework presented, a small group of physicians—working directly with government databases and applying Temporal Based Medicine—could resolve ongoing debates around COVID drugs and vaccines within weeks. Not years. Not decades. Weeks.

The Cost of Looking Away

The lecture closes by emphasizing what Acute Kidney Injury truly represents: not a temporary complication, but often a permanent injury that leads to lifelong dialysis, transplant dependence, or early death. The failure to recognize this signal in real time has long-term consequences, not only for patients, but for trust in medical decision-making itself. The records are already there. The question left hanging is who is willing to read them honestly, from beginning to end.